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Colonic neuroendocrine carcinoma in a child.

Identifieur interne : 002E35 ( Main/Exploration ); précédent : 002E34; suivant : 002E36

Colonic neuroendocrine carcinoma in a child.

Auteurs : RBID : pubmed:15565344

English descriptors

Abstract

A 10-year-old boy with congenital immunodeficiency (X-linked agammaglobulinaemia) presented with loss of appetite and weight, right-sided abdominal pain, diarrhoea and low-grade fever. Radiological investigations with barium follow-through, CT, PET and octreotide scans revealed a primary caecal/ascending proximal colonic mass with liver and bony metastases. Urine screen for 5HIAA was positive. Percutaneous liver biopsy confirmed the diagnosis of neuroendocrine carcinoma. The radiological work-up and the usefulness of various imaging modalities in the diagnosis of this rare paediatric tumour are discussed. The PET scan demonstrated the primary tumour and the metastatic locations more vividly than the octreotide scan, which is currently considered to be the most specific imaging modality for neuroendocrine masses.

DOI: 10.1007/s00247-004-1319-0
PubMed: 15565344

Links toward previous steps (curation, corpus...)


Le document en format XML

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<title xml:lang="en">Colonic neuroendocrine carcinoma in a child.</title>
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<name sortKey="Sasi, Omai Al" uniqKey="Sasi O">Omai Al Sasi</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Radiology, MBC#28, King Faisal Specialist Hospital and Research Centre, PO Box 3354, 11211, Riyadh, Saudi Arabia. dr_omaialsasi@hotmail.com</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>Department of Radiology, MBC#28, King Faisal Specialist Hospital and Research Centre, PO Box 3354, 11211, Riyadh</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Sathiapalan, Rajeev" uniqKey="Sathiapalan R">Rajeev Sathiapalan</name>
</author>
<author>
<name sortKey="Rifai, Ayman" uniqKey="Rifai A">Ayman Rifai</name>
</author>
<author>
<name sortKey="Tulbah, Asthma Mahmoud Mohamed" uniqKey="Tulbah A">Asthma Mahmoud Mohamed Tulbah</name>
</author>
<author>
<name sortKey="Al Mehaidib, Ali" uniqKey="Al Mehaidib A">Ali Al-Mehaidib</name>
</author>
<author>
<name sortKey="Kofide, Amani" uniqKey="Kofide A">Amani Kofide</name>
</author>
<author>
<name sortKey="Hugosson, Claes" uniqKey="Hugosson C">Claes Hugosson</name>
</author>
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<term>Biopsy</term>
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<term>Child</term>
<term>Colonic Neoplasms (radionuclide imaging)</term>
<term>Diagnosis, Differential</term>
<term>Gastrointestinal Agents (diagnostic use)</term>
<term>Humans</term>
<term>Indium Radioisotopes (diagnostic use)</term>
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<term>Octreotide (diagnostic use)</term>
<term>Positron-Emission Tomography</term>
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<term>Carcinoma, Neuroendocrine</term>
<term>Colonic Neoplasms</term>
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<keywords scheme="MESH" xml:lang="en">
<term>Biopsy</term>
<term>Child</term>
<term>Diagnosis, Differential</term>
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<front>
<div type="abstract" xml:lang="en">A 10-year-old boy with congenital immunodeficiency (X-linked agammaglobulinaemia) presented with loss of appetite and weight, right-sided abdominal pain, diarrhoea and low-grade fever. Radiological investigations with barium follow-through, CT, PET and octreotide scans revealed a primary caecal/ascending proximal colonic mass with liver and bony metastases. Urine screen for 5HIAA was positive. Percutaneous liver biopsy confirmed the diagnosis of neuroendocrine carcinoma. The radiological work-up and the usefulness of various imaging modalities in the diagnosis of this rare paediatric tumour are discussed. The PET scan demonstrated the primary tumour and the metastatic locations more vividly than the octreotide scan, which is currently considered to be the most specific imaging modality for neuroendocrine masses.</div>
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<Day>21</Day>
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<Month>11</Month>
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<ISSN IssnType="Print">0301-0449</ISSN>
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<Volume>35</Volume>
<Issue>3</Issue>
<PubDate>
<Year>2005</Year>
<Month>Mar</Month>
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<Title>Pediatric radiology</Title>
<ISOAbbreviation>Pediatr Radiol</ISOAbbreviation>
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<ArticleTitle>Colonic neuroendocrine carcinoma in a child.</ArticleTitle>
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<MedlinePgn>339-43</MedlinePgn>
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<Abstract>
<AbstractText>A 10-year-old boy with congenital immunodeficiency (X-linked agammaglobulinaemia) presented with loss of appetite and weight, right-sided abdominal pain, diarrhoea and low-grade fever. Radiological investigations with barium follow-through, CT, PET and octreotide scans revealed a primary caecal/ascending proximal colonic mass with liver and bony metastases. Urine screen for 5HIAA was positive. Percutaneous liver biopsy confirmed the diagnosis of neuroendocrine carcinoma. The radiological work-up and the usefulness of various imaging modalities in the diagnosis of this rare paediatric tumour are discussed. The PET scan demonstrated the primary tumour and the metastatic locations more vividly than the octreotide scan, which is currently considered to be the most specific imaging modality for neuroendocrine masses.</AbstractText>
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